Designed for specialist prescribers and clinicians, this advanced module delves into the clinical application of medical cannabis for complex pain management.
You will explore the neurobiology of the Endocannabinoid System in nociception and critically appraise the evidence base—ranging from systematic reviews to emerging Real-World Data (RWD). The course provides specific, evidence-based prescribing protocols for neuropathic, nociplastic, and palliative pain conditions.
By the end of this course you will be able to:
The Burden of Chronic Pain
Limitations of Conventional Therapy
Biology of Pain & The ECS
Overview of the Evidence Landscape
Pathophysiology of Chronic Pain
Critical Appraisal of Systematic Reviews
The Opioid Sparing Effect
UK Medical Cannabis Registry Outcomes
Nociceptive vs. Nociplastic Pain
Phase 3 RCT Evidence (VER-01)
Medical Cannabis vs. Opioids: Head-to-Head
Real-World Evidence & Challenges
Mechanisms: TRPV1 & Signal Modulation
Subgroup Analysis from Phase 3 Trials
Specific Conditions: MS & Diabetic Neuropathy
Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Central Sensitisation & The ECS
Evidence for Pain, Fatigue & Sleep
Safety Profile: Heightened Sensitivity
Managing Patient Expectations
The “Constant Acute Pain” Paradigm
Symptom Clusters in Palliative Care
Conflicting Evidence: RCTs vs. Real-World Data
Clinical Management & Licensed Products
Formulation Strategy: Oils vs. Inhaled
Dosing & Titration Protocols
Prescribing Pastilles & Dried Flower
Safety, Contraindications & Driving